Mid- to Late-Life Systemic Inflammation and Late-Life Cardiac Structure and Function: The Atherosclerosis Risk in Communities (ARIC) Study

Smoking and Cardiac Structure and Function in the Elderly: The ARIC Study (Atherosclerosis Risk in Communities).

BACKGROUND Cigarette smoking has been associated with higher risk of incident heart failure independent of coronary artery disease, but the impact of tobacco use on cardiac structure and function in the general population is uncertain. This study evaluated the relationship between smoking and echocardiographic measures in a large elderly cohort. METHODS AND RESULTS We studied 4580 participant...

Self-reported fatigue and physical function in late mid-life.

OBJECTIVE To determine the association between the 5 subscales of the Multidimensional Fatigue Inventory (MFI-20) and physical function in late mid-life. DESIGN Cross-sectional study. SUBJECTS A population-based sample of adults who participated in the Copenhagen Aging and Midlife Biobank population cohort (n = 4,964; age 49-63 years). METHODS Self-reported fatigue was measured using the ...

The Atherosclerosis Risk in Communities (ARIC) Study

Dysregulation of the autonomic nervous system has been implicated in the development of hypertension. Heart rate variability is a noninvasive tool to quantitatively estimate cardiac autonomic activity and has been used to document decreased cardiac autonomic activity in hypertension. The ability of decreased heart rate variability to predict incident hypertension has not been well studied, and ...

The Atherosclerosis Risk in Communities (ARIC) Study

Background and Purpose: The Atherosclerosis Risk in Communities Study is a prospective investigation of the etiology and natural history of atherosclerosis and the etiology of clinical disease in four US communities. Methods: Noninvasive ultrasonic methods were used to determine mean wall thickness (WT), radius (R), and circumferential arterial strain (CAS) in the left common carotid artery of ...

Relation Between Alcohol Consumption and Cardiac Structure and Function in the Elderly: The Atherosclerosis Risk in Communities (ARIC) Study